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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-1-14
pubmed:abstractText
The time course of brain-stem auditory evoked potential (BAEP) changes was investigated using an impact-acceleration trauma model in 23 spontaneously breathing rats. Intracranial pressure (ICP), arterial blood pressure and respiratory rate were monitored. The experiments were terminated at four hours after trauma. No significant changes in intracranial pressure (ICP) occurred following the impact. After a short increase, blood pressure returned to baseline values within 5 min. Transient apnea was not followed by prolonged respiratory depression. Diffuse closed head injury (CHI) did not result in general, unidirectional changes of peak latencies or amplitudes of auditory evoked responses. Most BAEP changes developed slowly reaching a maximum at 1 to 4 hours after the injury. In the absence of ICP changes, this pattern reflects secondary ischemia in sensitive brain-stem areas rather than direct traumatic lesions or hypoxia due to respiratory depression.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0065-1419
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
88-90
pubmed:dateRevised
2004-11-12
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Brain-stem auditory evoked potential monitoring in experimental diffuse brain injury.
pubmed:affiliation
Department of Neurosurgery, Nordstadt Hospital, Hannover, Federal Republic of Germany.
pubmed:publicationType
Journal Article