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rdf:type |
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lifeskim:mentions |
umls-concept:C0002518,
umls-concept:C0017337,
umls-concept:C0017428,
umls-concept:C0027610,
umls-concept:C0028630,
umls-concept:C0206419,
umls-concept:C0449719,
umls-concept:C0521346,
umls-concept:C0681842,
umls-concept:C1304890,
umls-concept:C1707455,
umls-concept:C2700640
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pubmed:issue |
1
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pubmed:dateCreated |
1998-12-2
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pubmed:databankReference |
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pubmed:abstractText |
The 3'-ends of the genomes (9538 bp) of two wild-type respiratory bovine coronavirus (RBCV) isolates LSU and OK were obtained by cDNA sequencing. In addition, the 3'-end of the genome (9545) of the wild-type enteric bovine coronavirus (EBCV) strain LY-138 was assembled from available sequences and by cDNA sequencing of unknown genomic regions. Comparative analyses of RBCV and EBCV nucleotide and deduced amino acid sequences revealed that RBCV-specific nucleotide and amino acid differences were disproportionally concentrated within the S gene and the genomic region between the S and E genes. Comparisons among virulent and avirulent BCV strains revealed that virulence-specific nucleotide and amino acid changes were located within the S and E genes, and the 32 kDa open reading frame.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0920-8569
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9778786-Amino Acid Sequence,
pubmed-meshheading:9778786-Animals,
pubmed-meshheading:9778786-Base Sequence,
pubmed-meshheading:9778786-Cattle,
pubmed-meshheading:9778786-Coronavirus, Bovine,
pubmed-meshheading:9778786-DNA, Viral,
pubmed-meshheading:9778786-Digestive System,
pubmed-meshheading:9778786-Genes, Viral,
pubmed-meshheading:9778786-Humans,
pubmed-meshheading:9778786-Membrane Glycoproteins,
pubmed-meshheading:9778786-Molecular Sequence Data,
pubmed-meshheading:9778786-Open Reading Frames,
pubmed-meshheading:9778786-Phylogeny,
pubmed-meshheading:9778786-Respiratory System,
pubmed-meshheading:9778786-Sequence Alignment,
pubmed-meshheading:9778786-Sequence Analysis, DNA,
pubmed-meshheading:9778786-Sequence Homology, Amino Acid,
pubmed-meshheading:9778786-Sequence Homology, Nucleic Acid,
pubmed-meshheading:9778786-Species Specificity,
pubmed-meshheading:9778786-Tumor Cells, Cultured,
pubmed-meshheading:9778786-Viral Envelope Proteins,
pubmed-meshheading:9778786-Viral Proteins,
pubmed-meshheading:9778786-Viral Structural Proteins,
pubmed-meshheading:9778786-Virulence
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pubmed:year |
1998
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pubmed:articleTitle |
Nucleotide and predicted amino acid sequences of all genes encoded by the 3' genomic portion (9.5 kb) of respiratory bovine coronaviruses and comparisons among respiratory and enteric coronaviruses.
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pubmed:affiliation |
Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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