Linked Life Data

9773356

Source:http://linkedlifedata.com/resource/pubmed/id/9773356

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-12-23
pubmed:abstractText
This article reviews the major neurobiologic effects of electroconvulsive therapy (ECT) implicated in its antidepressant actions. These effects are organized into three main groups: (1) the action of ECT on the monoamine neurotransmitter system, norepinephrine, serotonin, and dopamine; (2) the neurotrophic action of ECT; and (3) the anticonvulsant effect of ECT. This review emphasizes clinical studies, but relevant animal studies are used to infer more details about changes in neurotransmitter turnover, peptides, and changes in gene expression. There are significant differences in the actions of ECT compared with antidepressant medications, for example, on monoaminergic systems, which may explain why ECT is such an effective antidepressant.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1095-0680
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172-80
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Neurobiological correlates of the antidepressant action of electroconvulsive therapy.
pubmed:affiliation
Department of Neuroscience, New York State Psychiatric Institute, NY 10032, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review