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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-11-23
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pubmed:databankReference | |
pubmed:abstractText |
Pasteurella multocida is the aetiological agent of fowl cholera, bovine haemorrhagic septicaemia and atrophic rhinitis in pigs. Many strains of P. multocida express a capsule on their surface. However, nothing is known about the capsule biosynthetic locus in P. multocida although the capsule has been implicated as a virulence factor. The entire capsule locus of P. multocida A:1 was cloned and sequenced. The locus is divided into three regions. Region 1 comprises four ORFs which are involved in the transport of the capsule polysaccharide to the surface. Region 2 comprises five ORFs whose postulated protein products are involved in the biosynthesis of the polysaccharide capsule. Region 3 comprises two ORFs whose postulated products show similarity to proteins that are involved in the phospholipid substitution of the polysaccharide capsule.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0378-1097
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
289-96
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9770287-Amino Acid Sequence,
pubmed-meshheading:9770287-Bacterial Capsules,
pubmed-meshheading:9770287-Chromosome Mapping,
pubmed-meshheading:9770287-Genes, Bacterial,
pubmed-meshheading:9770287-Hyaluronic Acid,
pubmed-meshheading:9770287-Molecular Sequence Data,
pubmed-meshheading:9770287-Multigene Family,
pubmed-meshheading:9770287-Open Reading Frames,
pubmed-meshheading:9770287-Pasteurella multocida,
pubmed-meshheading:9770287-Plasmids,
pubmed-meshheading:9770287-Promoter Regions, Genetic,
pubmed-meshheading:9770287-Restriction Mapping,
pubmed-meshheading:9770287-Sequence Analysis, DNA,
pubmed-meshheading:9770287-Virulence
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pubmed:year |
1998
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pubmed:articleTitle |
The capsule biosynthetic locus of Pasteurella multocida A:1.
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pubmed:affiliation |
Department of Microbiology, Monash University, Clayton, Vic., Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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