Linked Life Data

9769106

Source:http://linkedlifedata.com/resource/pubmed/id/9769106

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-10-22
pubmed:abstractText
The use of biomarkers in toxicology is becoming increasingly important. This article briefly reviews some of the aspects in an attempt to give an overall view of the field. Some of the new developments, particularly in relation to biomarkers of exposure and response, are mentioned. Specific DNA and protein adducts can now be used as biomarkers of the effective exposure so incorporating variations in environmental levels and individual disposition. Analysis of urinary metabolite profiles by NMR can highlight novel markers and allow recognition of patterns of metabolite changes as biomarkers of a toxic response. Novel urinary markers for liver and testicular dysfunction are discussed. Finally, the acetylator phenotype as a biomarker of susceptibility is described.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0300-483X
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
129
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-12
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Biomarkers in toxicology.
pubmed:affiliation
Department of Pharmacy, King's College London, UK.
pubmed:publicationType
Journal Article, In Vitro, Review