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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4 Suppl 10
|
pubmed:dateCreated |
1998-10-20
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pubmed:abstractText |
Dexrazoxane prevents the dose-limiting cardiotoxicity of the anthracyclines without reducing their antitumor efficacy and without new adverse side effects. Dexrazoxane reduces the severity of gastrointestinal symptoms of the anthracycline containing combination doxorubicin, 5-fluorouracil, cyclophosphamide and most surprisingly and importantly, dexrazoxane increases the median survival time of advanced breast cancer responders to the doxorubicin, 5-fluorouracil, cyclophosphamide regimen. The median survival time is doubled as compared to controls to nearly 3 years.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0093-7754
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
25
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
48-54
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9768824-Adult,
pubmed-meshheading:9768824-Anthracyclines,
pubmed-meshheading:9768824-Antineoplastic Agents,
pubmed-meshheading:9768824-Breast Neoplasms,
pubmed-meshheading:9768824-Cardiovascular Agents,
pubmed-meshheading:9768824-Child,
pubmed-meshheading:9768824-Clinical Trials as Topic,
pubmed-meshheading:9768824-Heart Diseases,
pubmed-meshheading:9768824-Humans,
pubmed-meshheading:9768824-Razoxane
|
pubmed:year |
1998
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pubmed:articleTitle |
Overview and historical development of dexrazoxane.
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pubmed:affiliation |
Windleshaw House, Withyham, East Sussex, England.
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pubmed:publicationType |
Journal Article,
Review
|