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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1998-12-31
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pubmed:abstractText |
Mesangial cells (MC) are known to secrete various vasoactive substances that may control endothelial and epithelial cell growth. Therefore, the cell-cell interactions among these cells may be important in the control of renal function. However, the exact mechanisms of maintaining the cell-cell interactions are not yet understood. We have focused on the role of hepatocyte growth factor (HGF) in the regulation of cell-cell interactions, since HGF has many protective functions in the kidney. To investigate the role of HGF in renal injury, we examined (1) the effects of HGF on epithelial injury induced by serum deprivation, and (2) the role of local HGF production in the maintenance of renal structure.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1128-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9767528-Animals,
pubmed-meshheading:9767528-Apoptosis,
pubmed-meshheading:9767528-Base Sequence,
pubmed-meshheading:9767528-Cell Communication,
pubmed-meshheading:9767528-Cells, Cultured,
pubmed-meshheading:9767528-Coculture Techniques,
pubmed-meshheading:9767528-Culture Media, Serum-Free,
pubmed-meshheading:9767528-DNA Primers,
pubmed-meshheading:9767528-Dexamethasone,
pubmed-meshheading:9767528-Endothelium, Vascular,
pubmed-meshheading:9767528-Epithelial Cells,
pubmed-meshheading:9767528-Gene Expression,
pubmed-meshheading:9767528-Glomerular Mesangium,
pubmed-meshheading:9767528-Hepatocyte Growth Factor,
pubmed-meshheading:9767528-Humans,
pubmed-meshheading:9767528-Kidney,
pubmed-meshheading:9767528-Rats,
pubmed-meshheading:9767528-Swine,
pubmed-meshheading:9767528-Transfection,
pubmed-meshheading:9767528-Tumor Necrosis Factor-alpha
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pubmed:year |
1998
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pubmed:articleTitle |
Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells.
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pubmed:affiliation |
Department of Geriatric Medicine, Biomedical Research Center, Osaka University Medical School, Suita, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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