|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0020546,
umls-concept:C0026882,
umls-concept:C0030705,
umls-concept:C0330390,
umls-concept:C0332197,
umls-concept:C0384156,
umls-concept:C0596260,
umls-concept:C1549059,
umls-concept:C1552644,
umls-concept:C1711351,
umls-concept:C1823153,
umls-concept:C2349976
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pubmed:issue |
9
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|
pubmed:dateCreated |
1998-12-17
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|
pubmed:abstractText |
The pathophysiology of hypertensive crises is poorly understood. To date, no information is available about genetic determinants underlying the individual risk for development of hypertensive urgencies or emergencies. Recently, mutations in the beta subunit (h beta ENaC) and the gamma subunit (h gamma ENaC) of the human epithelial sodium channel (hENaC) have been shown to result in excessive elevation of blood pressure in patients with Liddle's syndrome.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-2972
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
707-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9767369-Adult,
pubmed-meshheading:9767369-Aged,
pubmed-meshheading:9767369-Aldosterone,
pubmed-meshheading:9767369-Amino Acid Sequence,
pubmed-meshheading:9767369-Base Sequence,
pubmed-meshheading:9767369-DNA,
pubmed-meshheading:9767369-Emergencies,
pubmed-meshheading:9767369-Female,
pubmed-meshheading:9767369-Humans,
pubmed-meshheading:9767369-Hypertension,
pubmed-meshheading:9767369-Male,
pubmed-meshheading:9767369-Middle Aged,
pubmed-meshheading:9767369-Molecular Sequence Data,
pubmed-meshheading:9767369-Mutation,
pubmed-meshheading:9767369-Polymerase Chain Reaction,
pubmed-meshheading:9767369-Potassium,
pubmed-meshheading:9767369-Protein Conformation,
pubmed-meshheading:9767369-Renin,
pubmed-meshheading:9767369-Sodium Channels
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pubmed:year |
1998
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pubmed:articleTitle |
Mutations in the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel are not present in patients with hypertensive crisis.
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pubmed:affiliation |
Department of Laboratory Medicine, University of Vienna, Austria. Manuela.Foedinger@akh-wien.ac.at
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pubmed:publicationType |
Journal Article
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