Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-12-21
pubmed:abstractText
Cell differentiation and proliferation are influenced by peptide growth factors. These peptide molecules are important in maintaining the normal development and growth of animal cells; in addition, they have been found to play a major role in disease states. The role of growth factors in the development of arteriosclerosis and intimal hyperplasia is of great interest to us as physicians taking care of patients with peripheral vascular disease. Factors such as platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), insulin, insulin-like growth factor-I (IGF-I), and transforming growth factors alpha and beta (TGF alpha and beta) have been found to play important roles in controlling the progression of cells in the cell cycle. Furthermore, various growth factors have been found to influence the motility of cells, particularly vascular smooth muscle cells (VSMCs).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0895-7967
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-55
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Peptide growth factors and signal transduction.
pubmed:affiliation
Department of Surgery, Veterans Affairs Medical Center, George Washington University, Washington, DC, USA.
pubmed:publicationType
Journal Article, Review