Linked Life Data

9760584

Source:http://linkedlifedata.com/resource/pubmed/id/9760584

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1998-12-3
pubmed:abstractText
Bioelectrical impedance (BIA), a prediction method for estimating body water compartments and body cell mass (BCM), is being increasingly used in studies of human immunodeficiency virus (HIV)-related wasting, but there are few validation studies of the method in this group. The aim of this study is to examine the relationship between impedance measurements and body water compartments in patients with advanced HIV disease, and to investigate whether the newer approaches of multifrequency BIA, BIA spectroscopy, logarithmic transformation using a parallel circuit model, and direct calculation from electrical theory offer any advantage over traditional single-frequency BIA. We measured total body water (TBW) by deuterium dilution and extracellular water by bromide dilution in 33 patients with advanced HIV disease. Intracellular water and BCM were calculated from these results. Impedance was measured over a range of frequencies using a multifrequency analyzer. The relationship between impedance index at various frequencies and body water compartments was assessed by correlation and linear regression. We found that impedance index at higher frequencies had a closer relationship to TBW (r = 0.86, standard error of the estimate [SEE] = 2.96 at 1000 kHz) and at lower frequencies a closer relationship to extracellular water (ECW) (r = 0.47, SEE = 3.13 at 0 kHz) than the traditional 50 kHz measurement (r = 0.84, SE = 3.11 for TBW; r = 0.44 SEE = 3.19 for ECW), but the differences were marginal and not statistically significant. None of the other novel approaches tested were significantly better than traditional single frequency measurement. The 50 kHz equation for BCM developed in this study [BCM (kg) = (0.360331 x Ht2/Z50) + (0.151123 x Wt)-2.95] may be useful to investigators using BIA for hIV-wasting studies.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0899-9007
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
658-66
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Bioelectrical impedance analysis in human immunodeficiency virus-infected patients: comparison of single frequency with multifrequency, spectroscopy, and other novel approaches.
pubmed:affiliation
St. George's Hospital Medical School, London, United Kingdom.
pubmed:publicationType
Journal Article, Comparative Study