Linked Life Data

9759327

Source:http://linkedlifedata.com/resource/pubmed/id/9759327

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1998-10-29
pubmed:abstractText
Until the more recent advances made in molecular biology, attempts to link synaptic plasticity and learning have focused on using LTP as a marker of learning-induced synaptic plasticity, where one has expected to observe the same magnitude of change in synaptic strength as that observed with artificial stimulation. To a large extent this approach has been frustrated by the fact that it is generally assumed that the representation of the memory traces is distributed throughout widespread networks of cells. By implication it is more likely that one would observe small distributed changes within a network; a formidable task to measure. In this review we describe how the advances in molecular biology give us both the tools to investigate the mechanisms of synaptic plasticity and to apply these to investigations of the underlying mechanisms in learning and the formation of memories that have until now remained out of our grasp.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0764-4469
pubmed:author
pubmed:issnType
Print
pubmed:volume
321
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-107
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
A molecular biological approach to synaptic plasticity and learning.
pubmed:affiliation
Laboratoire de neurobiologie de l'apprentissage et de la mémoire, CNRS Ura 1491, université Paris-Sud, Orsay, France. sabrina.davis@ibaic.u-psud.fr
pubmed:publicationType
Journal Article, Review