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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1998-12-1
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pubmed:abstractText |
IFN-gamma is a pleiotropic cytokine endowed with potent immunomodulatory effects whose expression was long considered to be restricted to T and NK cells. Only recently, it became evident that IFN-gamma production can also occur in other cell types, including monocyte/macrophages. However, the biological relevance of macrophage IFN-gamma is still unclear. The purpose of this article is to provide an overview of the collected evidence demonstrating IFN-gamma expression in macrophages and to discuss the possible biological significance of this cytokine production in the early phase of host response to infectious agents.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1359-6101
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
9
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
117-23
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9754706-Animals,
pubmed-meshheading:9754706-Cytokines,
pubmed-meshheading:9754706-Gene Expression Regulation,
pubmed-meshheading:9754706-Humans,
pubmed-meshheading:9754706-Infection,
pubmed-meshheading:9754706-Interferon-gamma,
pubmed-meshheading:9754706-Macrophages,
pubmed-meshheading:9754706-Mice,
pubmed-meshheading:9754706-Models, Biological
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pubmed:year |
1998
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pubmed:articleTitle |
IFN-gamma expression in macrophages and its possible biological significance.
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pubmed:affiliation |
Laboratory of Virology, Instituto Superiore di Sanità, Rome, Italy. gessani@virus1.net.iss.it
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pubmed:publicationType |
Journal Article,
Review
|