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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-11-5
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pubmed:abstractText |
Electroporation is a widely applied method for gene or protein transfer into cells, and it is also used for electrochemotherapy of cancer. During gene transfection studies, electroporation was found to decrease transiently susceptibility of some tumor cell lines to alloreactive cytotoxic T lymphocytes (CTL) or lymphokine-activated killer (LAK) cells. In each cell line electroporation induced c-fos mRNA. In K562 cells HSP70 mRNA induction also occurred. Expression of Grp78, Bcl-2, CD95/Fas, or major histocompatibility complex class I molecules was not affected by electroporation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
250
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
259-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9753617-Animals,
pubmed-meshheading:9753617-Coculture Techniques,
pubmed-meshheading:9753617-Cytotoxicity, Immunologic,
pubmed-meshheading:9753617-Electroporation,
pubmed-meshheading:9753617-Gene Transfer Techniques,
pubmed-meshheading:9753617-Humans,
pubmed-meshheading:9753617-Killer Cells, Lymphokine-Activated,
pubmed-meshheading:9753617-Mice,
pubmed-meshheading:9753617-Neoplasms,
pubmed-meshheading:9753617-Rats,
pubmed-meshheading:9753617-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:9753617-Tumor Cells, Cultured
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pubmed:year |
1998
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pubmed:articleTitle |
Reduced susceptibility of electroporated tumor cell lines to killing by cytotoxic lymphocytes.
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pubmed:affiliation |
Division of Immunogenetics, University of Göttingen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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