Linked Life Data

975116

Source:http://linkedlifedata.com/resource/pubmed/id/975116

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1976-12-30
pubmed:abstractText
4-O-beta-D-Galactopyranosyl-alpha,beta-D-glucopyranosylamine (lactosylamine), beta-D-gluco-, alpha- and beta-D-galacto-, and beta-D-manno-pyranosylamines were bound to the carbodiimide-activated carboxyl groups of lysozyme. Of the 11 free carboxyl groups of the protein, approximately 3 were substituted by alpha,beta-lactosylamine, and approximately 2 by the monohexosylamines. One of the 4 glycopeptides isolated from the tryptic digest of the lysozyme-lactosylamine conjugate was identical to synthetic 1-N-L-leucinoyl-4-O-beta-D-galactopyranosyl-beta-D-glucopyranosylamine, indicating the substitution of the carboxyl group of the C-terminal leucine residue. The isolation of a glycopeptide containing the aspartic acid residue in position 117 indicates that the second alpha,beta-lactosylamine residue is linked to the carboxyl group of this amino acid. Both of the 2 other glycopeptides contain the same free carboxyl groups (one glutamic and two aspartic acid residues in positions 35, 48, and 52, respectively). The third alpha,beta-lactosylamine residue seems to be linked to one of these carboxyl groups.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0008-6215
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-41
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Condensation of D-glycosamines with proteins].
pubmed:publicationType
Journal Article, English Abstract