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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1998-11-9
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pubmed:abstractText |
A rapid and simple high performance liquid chromatographic method is described and validated for the determination of lobenzarit disodium (CAS 64808-48-6) in a sustained release tablet formulation. The calibration graph was linear over the range 20-105 micrograms/ml. The sensitivity (discriminator capacity) was 2.079 micrograms/ml. The coefficient of variations for repeatability and reproducibility were less than 1.60% and 1.30%, respectively. The accuracy of the method did not depend on lobenzarit concentration in tablets. The mean recovery was found to be 100.62%. The method was selective, even when degradation products were present.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0004-4172
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
48
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
832-5
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9748712-Anthranilic Acids,
pubmed-meshheading:9748712-Antirheumatic Agents,
pubmed-meshheading:9748712-Chromatography, High Pressure Liquid,
pubmed-meshheading:9748712-Delayed-Action Preparations,
pubmed-meshheading:9748712-Reproducibility of Results,
pubmed-meshheading:9748712-Spectrophotometry, Ultraviolet
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pubmed:year |
1998
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pubmed:articleTitle |
High performance liquid chromatographic method for the determination of lobenzarit disodium in a sustained release tablet formulation.
|
pubmed:affiliation |
Center of Pharmaceutical Chemistry, Havana, Cuba.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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