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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
1998-11-30
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pubmed:abstractText |
Two new porphinoids, tolyporphins J (1) and K (2), have been isolated from the terrestrial cyanobacterium, Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The activities of tolyporphins J and K in cell sensitization and drug accumulation assays for multidrug resistance (MDR) reversal were compared with those of tolyporphin A. Unusual NMR spectroscopic shifts were observed for tolyporphin J (1) in CDCl3.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0163-3864
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1133-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9748382-Antibiotics, Antineoplastic,
pubmed-meshheading:9748382-Chromatography, High Pressure Liquid,
pubmed-meshheading:9748382-Cyanobacteria,
pubmed-meshheading:9748382-Drug Resistance, Multiple,
pubmed-meshheading:9748382-Drug Screening Assays, Antitumor,
pubmed-meshheading:9748382-Humans,
pubmed-meshheading:9748382-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9748382-Mass Spectrometry,
pubmed-meshheading:9748382-Porphyrins,
pubmed-meshheading:9748382-Spectrophotometry, Ultraviolet,
pubmed-meshheading:9748382-Tumor Cells, Cultured,
pubmed-meshheading:9748382-Vinblastine
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pubmed:year |
1998
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pubmed:articleTitle |
Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa.
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pubmed:affiliation |
Department of Chemistry, University of Waikato, Private Bag 3105, Hamilton, New Zealand. michele@waikato.ac.nz
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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