Linked Life Data

9746980

Source:http://linkedlifedata.com/resource/pubmed/id/9746980

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1998-12-22
pubmed:abstractText
With the new method of gas exchange and dialysis carried out simultaneously with a standard dialysis module, for the first time normothermic ex-vivo whole blood perfusion of pig kidneys becomes practicable under nearly physiological conditions. To show the possibility of animal experiment replacements we use slaughter house kidneys to investigate functional abilities of the perfusion method. Slaughter house kidneys show a state of acute ischemic renal failure due to the unavoidable time of ischemia and cold preservation. Nevertheless they show a specific functional metabolism up to 4 hours of perfusion time. For the future, the new perfusion model seems suitable to investigate acute organ rejection and perfusion phenomena on pig kidneys, which are most interesting for xenotransplantation.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0044-409X
pubmed:author
pubmed:issnType
Print
pubmed:volume
123
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
809-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Effect of blood viscosity on the function of isolated perfused porcine kidney after cold preservation].
pubmed:affiliation
Klinikum Virchow/Charité, Humboldt-Universität zu Berlin.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't