| pubmed-article:9744558 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0034715 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0010762 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0027310 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0053463 | lld:lifeskim |
| pubmed-article:9744558 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9744558 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:9744558 | pubmed:dateCreated | 1998-10-9 | lld:pubmed |
| pubmed-article:9744558 | pubmed:abstractText | We have recently reported that beta-ionone induces cytochrome P450 (P450) 2B1 in rats. Effects of beta-ionone on the expression of other P450 isozymes and NADPH-P450 reductase were further investigated in Sprague Dawley rats. Administration of beta-ionone subcutaneously 72 and 48 h before sacrificing the animals not only significantly induced the liver microsomal activities of P450-associated enzymes and NADPH-P450 reductase, but also clearly increased in the level of P450 1A1/2, P450 2C, and NADPH-P450 reductase proteins. The induction of P450 1A1/2 and 2C by beta-ionone was much greater in male than in female as measured by western immunoblotting. Reverse transcriptase-polymerase chain reactions showed that, in addition to P450 2B1 and 2B2 mRNAs, P450 1A2, 2C6 and NADPH-P450 reductase mRNAs were increased when beta-ionone was administered. Our previous and present results indicated that beta-ionone may induce several P450s and NADPH-P450 reductase by the accumulation of their corresponding mRNAs. | lld:pubmed |
| pubmed-article:9744558 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9744558 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9744558 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9744558 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:9744558 | pubmed:issn | 0009-2797 | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:RohJ KJK | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:RAOK HKH | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:YukC SCS | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:JeongT CTC | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:ChunY JYJ | lld:pubmed |
| pubmed-article:9744558 | pubmed:author | pubmed-author:HUH HHH | lld:pubmed |
| pubmed-article:9744558 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9744558 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:9744558 | pubmed:volume | 114 | lld:pubmed |
| pubmed-article:9744558 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9744558 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9744558 | pubmed:pagination | 97-107 | lld:pubmed |
| pubmed-article:9744558 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9744558 | pubmed:meshHeading | pubmed-meshheading:9744558-... | lld:pubmed |
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| pubmed-article:9744558 | pubmed:meshHeading | pubmed-meshheading:9744558-... | lld:pubmed |
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| pubmed-article:9744558 | pubmed:meshHeading | pubmed-meshheading:9744558-... | lld:pubmed |
| pubmed-article:9744558 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9744558 | pubmed:articleTitle | Effects of beta-ionone on the expression of cytochrome P450s and NADPH-cytochrome P450 reductase in Sprague Dawley rats. | lld:pubmed |
| pubmed-article:9744558 | pubmed:affiliation | Toxicology Research Center, Korea Research Institute of Chemical Technology, Yusung, Taejon, South Korea. | lld:pubmed |
| pubmed-article:9744558 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9744558 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
