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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1998-12-30
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pubmed:abstractText |
In neuronal activity recorded from human middle temporal gyrus during learning of associations between word pairs, a population was identified that had greater activity for associations that were learned rapidly during initial encoding compared to those learned slowly or not at all by an individual subject. This population can be separated from other neurons by the combination of inhibition during word reading when no learning is required and excitation during recent memory for words. These neurons are present in both hemispheres, predominately in deeper layers of cortex. During initial encoding, the increased activity appears at presentation of all word pairs but persists for several seconds only for the rapidly learned pairs, likely reflecting rehersal of items being learned. Human associative learning is related to activity of this specific population of "association" neurons, identified here for the first time.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0093-934X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1998 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
317-27
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9743545-Adult,
pubmed-meshheading:9743545-Association Learning,
pubmed-meshheading:9743545-Epilepsy,
pubmed-meshheading:9743545-Humans,
pubmed-meshheading:9743545-Intelligence Tests,
pubmed-meshheading:9743545-Middle Aged,
pubmed-meshheading:9743545-Neurons,
pubmed-meshheading:9743545-Temporal Lobe
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pubmed:year |
1998
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pubmed:articleTitle |
Neurons in human temporal cortex active with verbal associative learning.
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pubmed:affiliation |
Department of Neurological Surgery, University of Washington gojemann@u.washington.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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