Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-11-24
|
pubmed:abstractText |
To determine the absorption and biodistribution of iron from microencapsulated ferrous sulfate (SFE-171), used to fortify dairy products with iron, a comparative study in four groups of 30 mice each was carried out. In two of the groups, the absorption of iron from ferrous ascorbate in water (13.3 +/- 4.3%) and from ferrous sulfate in water (12.7 +/- 3.9%) was determined and taken as reference standards. In the third group the iron absorption from SFE-171 in milk was determined, giving a value of 12.1 +/- 4.2%, which statistically does not differ from the data obtained with either reference standard. In the fourth group, the absorption of iron from ferrous sulfate in milk showed a value of 7.7 +/- 3.4%, which statistically differs with a p < 0.01 from the data corresponding to the other three groups. The biodistribution studies showed that the iron from the SFE-171 follows the same metabolic pathway as the iron from the reference standards thus, giving a higher radioactivity percentage and radioactivity concentration in organs or systems, principally blood, that are closely related to iron metabolism. Our studies allow us to conclude that the iron from SFE-171 in milk follows the same behavior as the nonhemic iron, with a higher absorption than that of ferrous sulfate in milk.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0301-4800
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
381-9
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9742459-Absorption,
pubmed-meshheading:9742459-Animals,
pubmed-meshheading:9742459-Bone and Bones,
pubmed-meshheading:9742459-Drug Compounding,
pubmed-meshheading:9742459-Female,
pubmed-meshheading:9742459-Ferrous Compounds,
pubmed-meshheading:9742459-Food, Fortified,
pubmed-meshheading:9742459-Liver,
pubmed-meshheading:9742459-Mice,
pubmed-meshheading:9742459-Milk,
pubmed-meshheading:9742459-Muscles,
pubmed-meshheading:9742459-Skin,
pubmed-meshheading:9742459-Tissue Distribution
|
pubmed:year |
1998
|
pubmed:articleTitle |
Microencapsulated ferrous sulfate to fortify cow milk: absorption and distribution in mice.
|
pubmed:affiliation |
Physics Department, School of Pharmacy and Biochemistry, University of Buenos Aires, Argentina.
|
pubmed:publicationType |
Journal Article
|