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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-11-19
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pubmed:abstractText |
The protective effect of Anacardium occidentale aqueous extract against streptozotocin-induced diabetes was evaluated in rats. The rats were treated with 175 mg/kg of the extract per os, twice daily; beginning 2 days before streptozotocin (STZ) injection. A total of 3 days after STZ administration, there was a 48% increase in blood glucose level in pretreated rats, compared with a 208% increase in diabetic control rats treated with STZ alone. Furthermore, these pretreated animals presented no glycosuria, a normal weight gain and a non significant increase in food and fluid intake at the end of the treatment compared with the normal control. Diabetic control animals showed a positive glycosuria, body weight loss, a real polyphagia and polydypsia. These results indicate the protective role of Anacardium occidentale extract against the diabetogenic action of STZ.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0378-8741
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9741880-Animals,
pubmed-meshheading:9741880-Blood Glucose,
pubmed-meshheading:9741880-Diabetes Mellitus, Experimental,
pubmed-meshheading:9741880-Male,
pubmed-meshheading:9741880-Plant Extracts,
pubmed-meshheading:9741880-Plants, Medicinal,
pubmed-meshheading:9741880-Rats,
pubmed-meshheading:9741880-Rats, Wistar,
pubmed-meshheading:9741880-Streptozocin
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pubmed:year |
1998
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pubmed:articleTitle |
Protective role of Anacardium occidentale extract against streptozotocin-induced diabetes in rats.
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pubmed:affiliation |
Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde 1, Cameroon.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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