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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
1998-9-23
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pubmed:abstractText |
Non-steroidal anti-inflammatory drugs can reduce the risk of colorectal cancer. Reportedly, mRNA expression of cyclooxygenase-2 (COX-2) is elevated in human colorectal cancers compared with accompanying normal mucosa. The present study was undertaken to establish a simple analytical procedure to quantify COX-2 expression levels and to characterize COX-2 expression levels in human colorectal cancers, adenomas and hyperplastic polyps.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0368-2811
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pubmed:author |
pubmed-author:FujitaSS,
pubmed-author:GotodaTT,
pubmed-author:KakizoeTT,
pubmed-author:MaekawaMM,
pubmed-author:MiyazakiSS,
pubmed-author:OhkuraHH,
pubmed-author:SanoHH,
pubmed-author:SekiyaTT,
pubmed-author:SuganoKK,
pubmed-author:UshiamaMM,
pubmed-author:YokotaTT
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9739782-Adenoma,
pubmed-meshheading:9739782-Adult,
pubmed-meshheading:9739782-Aged,
pubmed-meshheading:9739782-Aged, 80 and over,
pubmed-meshheading:9739782-Amino Acid Sequence,
pubmed-meshheading:9739782-Colonic Neoplasms,
pubmed-meshheading:9739782-Colonic Polyps,
pubmed-meshheading:9739782-Female,
pubmed-meshheading:9739782-Humans,
pubmed-meshheading:9739782-Immunohistochemistry,
pubmed-meshheading:9739782-Intestinal Mucosa,
pubmed-meshheading:9739782-Male,
pubmed-meshheading:9739782-Middle Aged,
pubmed-meshheading:9739782-Molecular Sequence Data,
pubmed-meshheading:9739782-Polymerase Chain Reaction,
pubmed-meshheading:9739782-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:9739782-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:9739782-RNA, Messenger,
pubmed-meshheading:9739782-Rectal Neoplasms
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pubmed:year |
1998
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pubmed:articleTitle |
Increased expression of cyclooxygenase-2 to -1 in human colorectal cancers and adenomas, but not in hyperplastic polyps.
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pubmed:affiliation |
Division of Clinical Laboratory, National Cancer Center Research Institute, Tokyo, Japan. mmaekawa@gan2.ncc.go.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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