Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1998-11-23
|
| pubmed:databankReference | |
| pubmed:abstractText |
Development-dependent mRNA expression of the chloride channels ClC-2 and ICln was studied by quantitative reverse transcriptase-polymerase chain reaction in rat ureteric bud and cortical collecting duct primary monolayer cultures. Abundance of ClC-2 mRNA increased in ureteric bud cells between embryonic day 15 (E15) and E17, peaked at postnatal day 3 (P3), and was down-regulated at P7 when morphogenesis is complete, suggesting a specific embryonic function. Expression of ICln mRNA, in contrast, up-regulated continuously with development.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0098-6577
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
67
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
S149-51
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9736273-Animals,
pubmed-meshheading:9736273-Cells, Cultured,
pubmed-meshheading:9736273-Chloride Channels,
pubmed-meshheading:9736273-Epithelial Cells,
pubmed-meshheading:9736273-Gene Expression Regulation, Developmental,
pubmed-meshheading:9736273-Ion Channels,
pubmed-meshheading:9736273-Kidney Tubules, Collecting,
pubmed-meshheading:9736273-Molecular Sequence Data,
pubmed-meshheading:9736273-RNA, Messenger,
pubmed-meshheading:9736273-Rats,
pubmed-meshheading:9736273-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:9736273-Ureter
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Chloride channels ClC-2 and ICln mRNA expression differs in renal epithelial ontogeny.
|
| pubmed:affiliation |
Physiologisches Institut, Ludwig-Maximilians-Universität, Germany.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|