9734785

Source:http://linkedlifedata.com/resource/pubmed/id/9734785

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0105770, umls-concept:C0162832, umls-concept:C0244988, umls-concept:C0392756, umls-concept:C0441889, umls-concept:C1332359, umls-concept:C1704259, umls-concept:C1705987, umls-concept:C1710082, umls-concept:C1999216
pubmed:issue	6
pubmed:dateCreated	1998-11-13
pubmed:abstractText	The Wnt/Wingless signalling pathway plays an important role in both embryonic development and tumorigenesis. Beta-catenin and Axin are positive and negative effectors of the Wnt signalling pathway, respectively.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9607379
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adenomatous Polyposis Coli Protein, http://linkedlifedata.com/resource/pubmed/chemical/Axin Protein, http://linkedlifedata.com/resource/pubmed/chemical/CTNNB1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Calmodulin-Dependent..., http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins, http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Glycogen Synthase Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Glycogen Synthase Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators, http://linkedlifedata.com/resource/pubmed/chemical/Wnt Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Zebrafish Proteins, http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1356-9597
pubmed:author	pubmed-author:AkiyamaTT, pubmed-author:AnaiKK, pubmed-author:HamadaFF, pubmed-author:IshidateTT, pubmed-author:KawaharaKK, pubmed-author:NakamuraTT, pubmed-author:ToyoshimaKK
pubmed:issnType	Print
pubmed:volume	3
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	395-403
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:9734785-Adenomatous Polyposis Coli Protein, pubmed-meshheading:9734785-Axin Protein, pubmed-meshheading:9734785-Binding Sites, pubmed-meshheading:9734785-Calcium-Calmodulin-Dependent Protein Kinases, pubmed-meshheading:9734785-Cytoskeletal Proteins, pubmed-meshheading:9734785-GTP-Binding Proteins, pubmed-meshheading:9734785-Gene Expression Regulation, Neoplastic, pubmed-meshheading:9734785-Glycogen Synthase Kinase 3, pubmed-meshheading:9734785-Glycogen Synthase Kinases, pubmed-meshheading:9734785-Humans, pubmed-meshheading:9734785-Protein Binding, pubmed-meshheading:9734785-Proteins, pubmed-meshheading:9734785-Proto-Oncogene Proteins, pubmed-meshheading:9734785-Repressor Proteins, pubmed-meshheading:9734785-Signal Transduction, pubmed-meshheading:9734785-Trans-Activators, pubmed-meshheading:9734785-Tumor Cells, Cultured, pubmed-meshheading:9734785-Wnt Proteins, pubmed-meshheading:9734785-Zebrafish Proteins, pubmed-meshheading:9734785-beta Catenin
pubmed:year	1998
pubmed:articleTitle	Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level.
pubmed:affiliation	Department of Oncogene Research, Institute for Microbial Diseases, Osaka University, Suita, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't