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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-9-24
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pubmed:abstractText |
In hepatectomy for patients with liver cirrhosis or cholestasis, prolonged postoperative hyperbilirubinemia is a troublesome complication and, if uncontrolled, often leads to life-threatening hepatic failure. Hepatocyte growth factor (HGF), first identified as the most potent mitogen for primary hepatocytes, has been shown to have multiple biological properties on liver, including mitogenic, antifibrotic, and cytoprotective activities. This study investigated the beneficial effects of a perioperative HGF supply to jaundiced liver after hepatectomy in rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-4804
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1998 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
54-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9733618-Animals,
pubmed-meshheading:9733618-Cholestasis,
pubmed-meshheading:9733618-DNA,
pubmed-meshheading:9733618-Hepatectomy,
pubmed-meshheading:9733618-Hepatocyte Growth Factor,
pubmed-meshheading:9733618-Hyperbilirubinemia,
pubmed-meshheading:9733618-Liver Regeneration,
pubmed-meshheading:9733618-Male,
pubmed-meshheading:9733618-Rats,
pubmed-meshheading:9733618-Rats, Inbred F344,
pubmed-meshheading:9733618-Tumor Necrosis Factor-alpha
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pubmed:year |
1998
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pubmed:articleTitle |
Hepatocyte growth factor promotes liver regeneration with prompt improvement of hyperbilirubinemia in hepatectomized cholestatic rats.
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pubmed:affiliation |
Department of Surgery and Surgical Basic Science, Kyoto University School of Medicine, Kyoto, 606-8507, Japan.
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pubmed:publicationType |
Journal Article
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