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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1998-11-16
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pubmed:abstractText |
S-adenosylmethionine (SAMe) increases survival in alcoholic liver cirrhosis and may have a beneficial effect in cholestatic liver disease. SAMe repletes glutathione stores and protects tissue from oxygen free radicals. The effect of SAMe on bile acid-induced apoptosis is unknown. In the present study the possible hepatoprotective effect of SAMe was evaluated and compared with that of tauroursodeoxycholic acid (TUDCA).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-2972
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577-83
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:9726039-Animals,
pubmed-meshheading:9726039-Apoptosis,
pubmed-meshheading:9726039-Bile Acids and Salts,
pubmed-meshheading:9726039-Cell Nucleus,
pubmed-meshheading:9726039-Cell Survival,
pubmed-meshheading:9726039-Cells, Cultured,
pubmed-meshheading:9726039-DNA Fragmentation,
pubmed-meshheading:9726039-Dose-Response Relationship, Drug,
pubmed-meshheading:9726039-Liver,
pubmed-meshheading:9726039-Male,
pubmed-meshheading:9726039-Rats,
pubmed-meshheading:9726039-Rats, Wistar,
pubmed-meshheading:9726039-S-Adenosylmethionine,
pubmed-meshheading:9726039-Taurochenodeoxycholic Acid
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pubmed:year |
1998
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pubmed:articleTitle |
Effect of S-adenosylmethionine versus tauroursodeoxycholic acid on bile acid-induced apoptosis and cytolysis in rat hepatocytes.
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pubmed:affiliation |
Department of Medicine, University of Heidelberg, Germany.
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pubmed:publicationType |
Journal Article
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