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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-11-6
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pubmed:abstractText |
Azathioprine-induced veno-occlusive disease of the liver mainly described after kidney transplantation is as rare as severe with a high mortality due to acute portal hypertension and liver failure. A kidney-transplanted patient with severe azathioprine-induced veno-occlusive disease of the liver and worsening despite drug discontinuation was treated by emergency transjugular intrahepatic portosystemic shunt. Whereas the veno-occlusive disease was controlled, the patient developed severe intractable portosystemic encephalopathy successfully treated by a stent reducer maintaining a certain degree of portal diversion. Twelve months after transjugular intrahepatic portosystemic shunt, liver function was normalized and the stent was thrombosed with a subnormal liver histology. Thirty-six months after transjugular intrahepatic portosystemic shunt the patient is alive with normal liver function tests and kidney graft function. Transjugular intrahepatic portosystemic shunt for treatment of severe veno-occlusive disease of the liver is an alternative to tide the patient over until recovery of liver function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0301-0430
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
118-22
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:9725784-Adult,
pubmed-meshheading:9725784-Azathioprine,
pubmed-meshheading:9725784-Biopsy,
pubmed-meshheading:9725784-Hepatic Veno-Occlusive Disease,
pubmed-meshheading:9725784-Humans,
pubmed-meshheading:9725784-Immunosuppression,
pubmed-meshheading:9725784-Immunosuppressive Agents,
pubmed-meshheading:9725784-Kidney Transplantation,
pubmed-meshheading:9725784-Liver,
pubmed-meshheading:9725784-Male,
pubmed-meshheading:9725784-Portasystemic Shunt, Transjugular Intrahepatic
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pubmed:year |
1998
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pubmed:articleTitle |
Successful treatment of severe azathioprine-induced hepatic veno-occlusive disease in a kidney-transplanted patient with transjugular intrahepatic portosystemic shunt.
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pubmed:affiliation |
Centre Hépato-Biliaire, Faculté de Médecine Paris-Sud, France.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|