Linked Life Data

9719399

Source:http://linkedlifedata.com/resource/pubmed/id/9719399

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-11-17
pubmed:abstractText
Moderate alcohol consumption is associated with a reduced risk of coronary heart disease. In this study, postprandial changes in plasma lipids, high-density lipoprotein (HDL) composition and cholesteryl ester transfer protein (CETP) and lecithin: cholesterol acyltransferase (LCAT) activity levels were investigated in response to moderate alcohol consumption. A dose of 40 g of alcohol was consumed as beer, wine or spirits by eight healthy middle-aged men before and during dinner thus simulating social drinking. Lipid parameters were studied before, and at 1, 3, 5, 9, and 13 h after dinner. An alcohol-induced elevation of plasma triglycerides was observed at 3 and 5 h after dinner, but total plasma cholesterol and apolipoprotein B were hardly affected. HDL lipids changed during the postprandial phase after alcohol consumption, HDL triglycerides were elevated at 5 and 9 h, HDL phospholipids were elevated at 9 and 13 h, and HDL cholesterol was elevated at 13 h. A 6% increase in the concentration of apolipoprotein A-II was observed at 13 h. Plasma LCAT activity was slightly increased 9 h after dinner, but CETP activity levels were not affected. The LCAT changes appeared similar for all three alcoholic beverages. It is concluded that moderate alcohol consumption with dinner affects plasma triglyceride concentration as well as HDL composition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0735-0414
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Moderate doses of alcoholic beverages with dinner and postprandial high density lipoprotein composition.
pubmed:affiliation
Department of Physiology, TNO Nutrition and Food Research Institute, Zeist, The Netherlands.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't