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rdf:type |
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lifeskim:mentions |
umls-concept:C0013080,
umls-concept:C0016617,
umls-concept:C0024915,
umls-concept:C0025118,
umls-concept:C0031809,
umls-concept:C0032979,
umls-concept:C0035647,
umls-concept:C0220908,
umls-concept:C0521457,
umls-concept:C1135241,
umls-concept:C1257890,
umls-concept:C1280412,
umls-concept:C1709701
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pubmed:issue |
9125
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|
pubmed:dateCreated |
1998-9-8
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|
pubmed:abstractText |
Prenatal diagnosis of trisomy 21 currently relies on assessment of risk followed by invasive testing in the 5% of pregnancies at the highest estimated risk. Selection of the high-risk group by a combination of maternal age and second-trimester maternal serum biochemistry gives a detection rate of about 60%. We investigated assessment of risk by a combination of maternal age and fetal nuchal-translucency thickness, measured by ultrasonography at 10-14 weeks of gestation.
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pubmed:commentsCorrections |
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pubmed:keyword |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0140-6736
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
352
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9717920-Adolescent,
pubmed-meshheading:9717920-Adult,
pubmed-meshheading:9717920-Chromosome Aberrations,
pubmed-meshheading:9717920-Chromosome Disorders,
pubmed-meshheading:9717920-Crown-Rump Length,
pubmed-meshheading:9717920-Down Syndrome,
pubmed-meshheading:9717920-Female,
pubmed-meshheading:9717920-Fetus,
pubmed-meshheading:9717920-Follow-Up Studies,
pubmed-meshheading:9717920-Gestational Age,
pubmed-meshheading:9717920-Great Britain,
pubmed-meshheading:9717920-Humans,
pubmed-meshheading:9717920-Karyotyping,
pubmed-meshheading:9717920-Likelihood Functions,
pubmed-meshheading:9717920-Maternal Age,
pubmed-meshheading:9717920-Middle Aged,
pubmed-meshheading:9717920-Neck,
pubmed-meshheading:9717920-Phenotype,
pubmed-meshheading:9717920-Predictive Value of Tests,
pubmed-meshheading:9717920-Pregnancy,
pubmed-meshheading:9717920-Pregnancy Outcome,
pubmed-meshheading:9717920-Pregnant Women,
pubmed-meshheading:9717920-Prevalence,
pubmed-meshheading:9717920-Risk Assessment,
pubmed-meshheading:9717920-Sensitivity and Specificity,
pubmed-meshheading:9717920-Ultrasonography, Prenatal
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pubmed:year |
1998
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pubmed:articleTitle |
UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation. Fetal Medicine Foundation First Trimester Screening Group.
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pubmed:affiliation |
Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London, UK.
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pubmed:publicationType |
Journal Article,
Comment,
Research Support, Non-U.S. Gov't,
Multicenter Study
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