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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1976-12-3
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pubmed:abstractText |
Plasma prostaglandin F 2-alpha (PGF 2-alpha) concentrations were compared in nine ovulatory dysmenorrheic women, one dysmenorrheic oral contraceptive user, and two nondysmenorrheic control subjects, in an effort to demonstrate a relationship between plasma PGF 2-alpha levels and dysmenorrhea. In addition, the effects of aspirin, a known inhibitorof prostaglandins synthesis, on dysmenorrhea and on PGF 2-alpha levels were investigated. No statistical difference was demonstrated between the plasma PGF 2-alpha levels of dysmenorrheic and nondysmenorrheic subjects throughout the menstrual cycle. Attainment of an adequate salicylate level was accompanied by a significant decrease in PGF 2-alpha levels. All dysmenorrheic subjects reported improvement in symptoms while taking aspirin. The greatest subjective relief was reported by women who began taking aspirin (10 grains every 4 hours) 3 or more days prior to the onset of bleeding.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0015-0282
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1171-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:971774-Adult,
pubmed-meshheading:971774-Aspirin,
pubmed-meshheading:971774-Dysmenorrhea,
pubmed-meshheading:971774-Female,
pubmed-meshheading:971774-Humans,
pubmed-meshheading:971774-Luteinizing Hormone,
pubmed-meshheading:971774-Menstruation,
pubmed-meshheading:971774-Progestins,
pubmed-meshheading:971774-Prostaglandins F
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pubmed:year |
1976
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pubmed:articleTitle |
Plasma prostaglandin F 2-alpha levels in dysmenorrehic women.
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pubmed:publicationType |
Journal Article
|