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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1998-11-6
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pubmed:abstractText |
It is desirable to shorten expose time in 3H-autoradiography. We developed a new solid scintillator, a mixture of DPO, POPOP and Epon 812, for whole-body autoradiography. The new scintillator is originally in a sol form, but quickly transforms to a solid homogeneous film following exposure to room air. The new scintillator enabled whole-body autoradiography to be developed faster when compared with a liquid scintillator or commercially available reagents. We also demonstrated that the new scintillator gave consistently high counting performance and thus shortened duration of exposure when used in whole-body autoradiography, whereas commercially available enhancers were found to be unsuitable for autoradiography, resulting in dappled images. Furthermore the quantitative analyses of the autoradiograms by a densitometer demonstrated the highest density, and ratio with this new solid scintillator among those with a liquid scintillator and commercially available reagents. In conclusion, a new solid scintillator, a mixture of DPO, POPOP and Epon 812, is a useful and cost effective enhancer for the whole-body autoradiography of tritum compounds.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,5-diphenyloxazole,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/EPON,
http://linkedlifedata.com/resource/pubmed/chemical/Epoxy Resins,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Oxazoles,
http://linkedlifedata.com/resource/pubmed/chemical/POPOP,
http://linkedlifedata.com/resource/pubmed/chemical/Suramin,
http://linkedlifedata.com/resource/pubmed/chemical/Tritium
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0916-7250
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
795-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9713805-Animals,
pubmed-meshheading:9713805-Antineoplastic Agents,
pubmed-meshheading:9713805-Autoradiography,
pubmed-meshheading:9713805-Epoxy Resins,
pubmed-meshheading:9713805-Humans,
pubmed-meshheading:9713805-Indicators and Reagents,
pubmed-meshheading:9713805-Male,
pubmed-meshheading:9713805-Mice,
pubmed-meshheading:9713805-Mice, Nude,
pubmed-meshheading:9713805-Oxazoles,
pubmed-meshheading:9713805-Prostatic Neoplasms,
pubmed-meshheading:9713805-Scintillation Counting,
pubmed-meshheading:9713805-Suramin,
pubmed-meshheading:9713805-Transplantation, Heterologous,
pubmed-meshheading:9713805-Tritium
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pubmed:year |
1998
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pubmed:articleTitle |
The role of a new liquid-solid scintillator, a mixture of DPO, POPOP and Epon 812, for enhancement of autoradiograms with tritium agents.
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pubmed:affiliation |
Department of Radioisotope Center, Kitasato University School of Medicine, Kanagawa, Japan.
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pubmed:publicationType |
Journal Article
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