rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1998-10-5
|
pubmed:abstractText |
The role of T cells carrying the killer cell inhibitory receptor (KIR) is unknown. Here we investigate the allo-response of KIR+ CD3+ cells (KIR+ T cells). KIR+ T cells was found in 4.6-14.7% of the T cells from the PBMC of healthy individuals. Flow cytometry analysis showed that the percentage of KIR+ T cells in T cells from three individuals was decreased after stimulation with allogeneic PBMC. These findings suggest that KIR+ T cells do not respond to alloantigens. Furthermore, the analyses using purified KIR+ T cells also confirmed that KIR+ T cells do not respond to alloantigens.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3,
http://linkedlifedata.com/resource/pubmed/chemical/Isoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, KIR
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0198-8859
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
59
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
488-92
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9712352-Antibodies, Monoclonal,
pubmed-meshheading:9712352-Antigens, CD3,
pubmed-meshheading:9712352-Flow Cytometry,
pubmed-meshheading:9712352-Humans,
pubmed-meshheading:9712352-Isoantigens,
pubmed-meshheading:9712352-Killer Cells, Natural,
pubmed-meshheading:9712352-Lymphocyte Activation,
pubmed-meshheading:9712352-Receptors, Antigen, T-Cell,
pubmed-meshheading:9712352-Receptors, Immunologic,
pubmed-meshheading:9712352-Receptors, KIR,
pubmed-meshheading:9712352-T-Lymphocytes
|
pubmed:year |
1998
|
pubmed:articleTitle |
T cells expressing killer cell inhibitory receptors do not carry TCR for alloantigens.
|
pubmed:affiliation |
Department of Tumor Biology, Institute of Medical Science, University of Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|