Linked Life Data

9711782

Source:http://linkedlifedata.com/resource/pubmed/id/9711782

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14-15
pubmed:dateCreated
1998-10-22
pubmed:abstractText
Most of our knowledge concerning the presence of virus specific cytotoxic T lymphocytes (CTL) in early life has been provided by studies of CTL activities against human immunodeficiency virus type 1 (HIV-1) in infected infants born to HIV-infected mothers. HIV-specific cytolytic responses were found to be similar in perinatally infected children compared with adults, with respect to the nature of effector cells, protein recognized and the ability to control viral replication. CTL responses measured immediately after PBMC isolation (ex vivo activated CTL) were observed predominantly in children with no or mild symptoms, and the presence of in vitro activated CTL was found to be associated with the absence of severe symptoms during the first year of life and survival over 5 years.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0264-410X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1420-2
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Cytotoxic T lymphocytes generation capacity in early life with particular reference to HIV.
pubmed:affiliation
Unité de Virologie et Immunologie Cellulaire, Institut Pasteur, Paris, France. riviere@pasteur.fr
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't