|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003765,
umls-concept:C0030685,
umls-concept:C0032143,
umls-concept:C0086418,
umls-concept:C0205178,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1515655,
umls-concept:C1518332,
umls-concept:C1880177,
umls-concept:C1963578
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1998-9-15
|
|
pubmed:abstractText |
Effective endogenous fibrinolysis requires rapid release of endothelial tissue plasminogen activator (t-PA). Using the nitric oxide synthase inhibitor, L-NG-monomethylarginine (L-NMMA), we examined the contribution of endogenous nitric oxide to substance P-induced t-PA release in vivo in man.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0008-6363
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
38
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
485-92
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:9709410-Adult,
pubmed-meshheading:9709410-Analysis of Variance,
pubmed-meshheading:9709410-Area Under Curve,
pubmed-meshheading:9709410-Dose-Response Relationship, Drug,
pubmed-meshheading:9709410-Forearm,
pubmed-meshheading:9709410-Humans,
pubmed-meshheading:9709410-Male,
pubmed-meshheading:9709410-Nitric Oxide Synthase,
pubmed-meshheading:9709410-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:9709410-Plethysmography,
pubmed-meshheading:9709410-Regional Blood Flow,
pubmed-meshheading:9709410-Substance P,
pubmed-meshheading:9709410-Tissue Plasminogen Activator,
pubmed-meshheading:9709410-omega-N-Methylarginine
|
|
pubmed:year |
1998
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|
pubmed:articleTitle |
The L-arginine/nitric oxide pathway contributes to the acute release of tissue plasminogen activator in vivo in man.
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|
pubmed:affiliation |
Clinical Pharmacology Unit and Research Centre, University of Edinburgh, Western General Hospital, UK. d.e.newby@ed.ac.uk
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
