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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
1998-9-17
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pubmed:abstractText |
Eight randomized controlled trials (RCTs) of screening mammography have been conducted involving women aged 40-49 at entry. Current data are now available from these trials at 10.5 to 18 years of follow-up (average follow-up time: 12.7 years). Meta-analysis has been performed using a Mantel-Haenszel estimator method to combine current follow-up data from the eight RCTs of mammography that included women aged 40-49 at entry, including new follow-up data presented at the NIH Consensus Development Conference held January 21-23, 1997. Combining the most recent follow-up data on women aged 40-49 at entry into all eight RCTs yields a statistically significant 18% mortality reduction among women invited to screening mammography (relative risk: 0.82; 95% confidence interval: 0.71-0.95). Combining all current follow-up data on women aged 40-49 at entry into the five Swedish RCTs yields a statistically significantly 29% mortality reduction among women invited to screening (relative risk: 0.71; 95% confidence interval: 0.57-0.89). Meta-analysis including the most recent follow-up data from all eight RCTs involving women aged 40-49 at entry demonstrates for the first time a statistically significant mortality reduction due to regular screening mammography in women of this age group.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1052-6773
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-92
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9709282-Adult,
pubmed-meshheading:9709282-Breast Neoplasms,
pubmed-meshheading:9709282-Female,
pubmed-meshheading:9709282-Humans,
pubmed-meshheading:9709282-Likelihood Functions,
pubmed-meshheading:9709282-Mammography,
pubmed-meshheading:9709282-Mass Screening,
pubmed-meshheading:9709282-Middle Aged,
pubmed-meshheading:9709282-Randomized Controlled Trials as Topic,
pubmed-meshheading:9709282-Risk Assessment,
pubmed-meshheading:9709282-Survival Rate
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pubmed:year |
1997
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pubmed:articleTitle |
Benefit of screening mammography in women aged 40-49: a new meta-analysis of randomized controlled trials.
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pubmed:affiliation |
Department of Radiology, University of Colorado Health Sciences Center, Denver 80262, USA.
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pubmed:publicationType |
Journal Article,
Meta-Analysis
|