Linked Life Data

9707471

Source:http://linkedlifedata.com/resource/pubmed/id/9707471

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-10-20
pubmed:abstractText
Mammals have two genes (SRY and DMT1) for testis formation-androgenesis, an anti-testis gene, DAX1, an anti-Müllerian duct hormone, and steroid sex hormones. Drosophila uses the sex-lethal, transformer, and doublesex genes for sexual differentation and is supposed to lack sex hormones. However, the statement that insects do not have sex hormones loses much of its credibility if one considers (1) the classical endocrinological work on sexual differentiation in the firefly Lampyris and in the hevea tussock moth Orgyia; (2) the recent identification of an androgenic hormone and its role in sex determination in the isopod Armadillidium; (3) the similarity between steroidogenic factor 1 (SF-1) of mammals and fushi tarazu factor 1 (FTZ-F1) of Drosophila; and (4) the steroidogenic effect of gonadotropins secreted by the brain of female locusts and mosquitoes and of male gypsy moth. In our model, based on data from the literature, ecdysone, when present in high concentrations, might function as an androgenic sex steroid. It is also the precursor of 20-OH-ecdysone, which is the moulting hormone of insects, and in vitellogenic females of many species, the counterpart of estrogens as well. Other gender-specific hormones are likely to exist in the brain-gonad axis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0016-6480
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press.
pubmed:issnType
Print
pubmed:volume
111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
245-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
"Insects do not have sex hormones": a myth?
pubmed:affiliation
Zoological Institute, Katholieke Universiteit Leuven, Leuven, Belgium. arnold.deloof@bio.kuleuven.ac.be
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't