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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1998-8-19
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pubmed:abstractText |
Positron emission tomography (PET) allows the measurement of benzodiazepine-gamma-aminobutyric acidA (GABA(A)) receptor kinetics. We employed flumazenil radiolabeled with carbon 11, a radioligand that labels the benzodiazepine site on the GABA(A) receptor, and fully quantitative, high-sensitivity PET to test the hypothesis that central benzodiazepine site binding is decreased in medication-free patients with panic disorder.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-990X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
715-20
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:9707382-Adult,
pubmed-meshheading:9707382-Aged,
pubmed-meshheading:9707382-Brain,
pubmed-meshheading:9707382-Carbon Radioisotopes,
pubmed-meshheading:9707382-Cerebral Cortex,
pubmed-meshheading:9707382-Female,
pubmed-meshheading:9707382-Flumazenil,
pubmed-meshheading:9707382-Functional Laterality,
pubmed-meshheading:9707382-Humans,
pubmed-meshheading:9707382-Male,
pubmed-meshheading:9707382-Middle Aged,
pubmed-meshheading:9707382-Panic Disorder,
pubmed-meshheading:9707382-Personality Inventory,
pubmed-meshheading:9707382-Receptors, GABA-A,
pubmed-meshheading:9707382-Sex Factors,
pubmed-meshheading:9707382-Tissue Distribution,
pubmed-meshheading:9707382-Tomography, Emission-Computed,
pubmed-meshheading:9707382-gamma-Aminobutyric Acid
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pubmed:year |
1998
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pubmed:articleTitle |
Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.
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pubmed:affiliation |
Cyclotron Unit, Medical Research Council, Clinical Research Centre, Hammersmith Hospital, London, England.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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