Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1998-9-3
pubmed:abstractText
There is strong evidence accumulating that chronic infection with Helicobacter pylori (H. pylori) interferes with inhibitory pathways of the regulation of acid secretion. The increase in maximum acid output (MAO), and the increase in the sensitivity of the parietal cell to gastrin commonly observed in patients suffering from duodenal ulcer disease (DU), however, remains largely unexplained. Insufficient evidence is available concerning how these parameters are influenced by H. pylori infection in patients not suffering from peptic ulcer disease (PUD) and how they are related to H. pylori-induced gastritis. The aim of this study was to compare basal gastric acid secretion (BAO), MAO, and the sensitivity of the parietal cell to gastrin in H. pylori-positive and H. pylori-negative patients not suffering from PUD, and to study the relationship with their individual postprandial gastrin release and the degree of gastric antral and corpus gastritis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9270
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1277-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9707051-Adult, pubmed-meshheading:9707051-Biopsy, pubmed-meshheading:9707051-Dose-Response Relationship, Drug, pubmed-meshheading:9707051-Female, pubmed-meshheading:9707051-Gastric Acid, pubmed-meshheading:9707051-Gastric Acidity Determination, pubmed-meshheading:9707051-Gastric Mucosa, pubmed-meshheading:9707051-Gastrins, pubmed-meshheading:9707051-Gastritis, pubmed-meshheading:9707051-Helicobacter Infections, pubmed-meshheading:9707051-Helicobacter pylori, pubmed-meshheading:9707051-Humans, pubmed-meshheading:9707051-Linear Models, pubmed-meshheading:9707051-Male, pubmed-meshheading:9707051-Middle Aged, pubmed-meshheading:9707051-Pentagastrin, pubmed-meshheading:9707051-Peptic Ulcer, pubmed-meshheading:9707051-Postprandial Period, pubmed-meshheading:9707051-Statistics, Nonparametric, pubmed-meshheading:9707051-Stimulation, Chemical
pubmed:year
1998
pubmed:articleTitle
Effects of Helicobacter pylori on gastritis, pentagastrin-stimulated gastric acid secretion, and meal-stimulated plasma gastrin release in the absence of peptic ulcer disease.
pubmed:affiliation
Gastrointestinal Unit, Inselspital, Berne, Switzerland.
pubmed:publicationType
Journal Article, Comparative Study