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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1998-11-12
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pubmed:abstractText |
Increased concentrations of neutrophils and alveolar macrophages are recovered in the bronchoalveolar lavage (BAL) of smokers compared with non-smokers. We designed a study to determine the relationship between neutrophils and alveolar macrophages recovered by BAL and the degree of air-flow obstruction, measured by spirometry (chronic air-flow obstruction was defined as: FEV1 < 80% of predicted and FEV1/FVC ratio < 70% of predicted) in healthy smokers. We found a significant correlation between spirometric values and the number of neutrophils and alveolar macrophages in BAL fluid obtained from healthy smokers. Our findings suggest that counts of 13-15x1000 neutrophils/ml and/or 430-450x1000 alveolar macrophages/ml in BAL fluid could be used as markers of air-flow obstruction in smokers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0258-851X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
427-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9706495-Adult,
pubmed-meshheading:9706495-Airway Obstruction,
pubmed-meshheading:9706495-Bronchi,
pubmed-meshheading:9706495-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:9706495-Cell Survival,
pubmed-meshheading:9706495-Female,
pubmed-meshheading:9706495-Humans,
pubmed-meshheading:9706495-Macrophages, Alveolar,
pubmed-meshheading:9706495-Male,
pubmed-meshheading:9706495-Middle Aged,
pubmed-meshheading:9706495-Neutrophils,
pubmed-meshheading:9706495-Smoking,
pubmed-meshheading:9706495-Spirometry
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pubmed:articleTitle |
Bronchoalveolar lavage in smokers: quantification of alveolar macrophages and neutrophils as markers of bronchial obstruction.
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pubmed:affiliation |
Department of Pneumology, Hospital Princesa, Madrid, Spain. c.jimenez/princesa@hup.es
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pubmed:publicationType |
Journal Article
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