Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-10-15
|
pubmed:abstractText |
To determine the effect of extending the duration of ammonia (2% dry matter basis) treatment from 1 to 5 wk on the toxicity of endophyte-infected tall fescue seed, 60 male Harlan Sprague-Dawley rats were randomly assigned to the following six treatments during a 28-d trial: endophyte-free (E-), endophyte-infected (E+), 1 wk ammoniated endophyte-free (1AE-), 1 wk ammoniated endophyte-infected (1AE+), 5 wk ammoniated endophyte-free (5AE-), and 5 wk ammoniated endophyte-infected (5AE+) tall fescue seed. The concentration of total pyrrolizidine alkaloids (N-acetyl and N-formyl loline) of E+ fescue was reduced from 4203 micrograms/g to 3009 and 2533 micrograms/g by the 1AE+ and 5AE+ treatments, respectively. Ergovaline was lowered from 3.77 to 1.57 micrograms/g by 1AE+ and eliminated by 5AE+. Endophyte-infected treatment groups had depressed (P < 0.0001) daily feed intakes (DFI), daily weight gains (DWG), feed efficiencies (G/F), primary antibody responses, and T cell and B cell mitogenic responses than endophyte-free treatment groups. Ammoniation of endophyte-infected fescue seed improved DFI and DWG (P < 0.0001) and G/F (P < 0.05); however, there was no difference in performance criteria between the 1-wk and 5-wk ammoniation treatments. Endophyte-induced depressions in immune function were not alleviated by ammoniation.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0148-0545
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
387-404
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9706468-Acremonium,
pubmed-meshheading:9706468-Ammonia,
pubmed-meshheading:9706468-Animals,
pubmed-meshheading:9706468-Antibody Formation,
pubmed-meshheading:9706468-Body Weight,
pubmed-meshheading:9706468-Lymphocyte Activation,
pubmed-meshheading:9706468-Male,
pubmed-meshheading:9706468-Organ Size,
pubmed-meshheading:9706468-Plant Poisoning,
pubmed-meshheading:9706468-Poaceae,
pubmed-meshheading:9706468-Pyrrolizidine Alkaloids,
pubmed-meshheading:9706468-Rats,
pubmed-meshheading:9706468-Rats, Sprague-Dawley,
pubmed-meshheading:9706468-Seeds,
pubmed-meshheading:9706468-Spleen
|
pubmed:year |
1998
|
pubmed:articleTitle |
Comparison of two ammoniation procedures to reduce the toxicity of endophyte-infected tall fescue seed fed to rats.
|
pubmed:affiliation |
Department of Animal Sciences, University of Kentucky, Lexington 40546, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Corrected and Republished Article
|