Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1998-10-22
|
| pubmed:abstractText |
About 2,000 patients with primary CNS cancers, as defined by the ICD-O, were registered in four adjacent cancer registries in South and East Netherlands in 1989-1994, covering a population of more than 5 million people. About 85% of the patients were registered through pathological laboratories, concentrated in four centers for neurosurgery. Patients with a clinical-radiological diagnosis only (about 50% in the age-group of 75 years and older) were mainly identified through medical records of hospitalized patients. World-standardized incidence rates of 6.5 and 4.4 per 100,000 person-years for males and females, respectively, were similar to those reported in other European cancer registries. Eighty-five percent of histologically verified primary CNS cancers were of glial origin, 6% were lymphomas and 4% embryonal tumors. Gliomas were mainly of astrocytic (about 85%) and oligodendroglial or mixed type (about 10%). Without additional review most astrocytic tumors could be classified into high-grade (70-75%) and low-grade astrocytomas (20-25%). Different grading systems were used for gliomas, but the dichotomy of astrocytomas according to differentiation grade seemed to correspond well with the definition of the WHO. Age-specific incidence rates for low-grade astrocytomas were remarkably constant. The incidence of high-grade astrocytomas increased sharply with age and declined after the age of 70, whereas the incidence of clinically diagnosed tumors continued to increase. Male/females-ratios were relatively high for these tumor types (1. 6-1.7). We conclude that the registration of primary CNS cancers in the Netherlands may be almost complete and valid for gliomas, embryonal tumors and lymphomas.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0251-5350
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
247-57
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9705584-Adolescent,
pubmed-meshheading:9705584-Adult,
pubmed-meshheading:9705584-Age Distribution,
pubmed-meshheading:9705584-Aged,
pubmed-meshheading:9705584-Aged, 80 and over,
pubmed-meshheading:9705584-Central Nervous System Neoplasms,
pubmed-meshheading:9705584-Child,
pubmed-meshheading:9705584-Child, Preschool,
pubmed-meshheading:9705584-Female,
pubmed-meshheading:9705584-Humans,
pubmed-meshheading:9705584-Incidence,
pubmed-meshheading:9705584-Infant,
pubmed-meshheading:9705584-Infant, Newborn,
pubmed-meshheading:9705584-Male,
pubmed-meshheading:9705584-Middle Aged,
pubmed-meshheading:9705584-Netherlands,
pubmed-meshheading:9705584-Retrospective Studies,
pubmed-meshheading:9705584-Sex Distribution
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Incidence of primary central nervous system cancers in South and East Netherlands in 1989-1994.
|
| pubmed:affiliation |
Comprehensive Cancer Center South (IKZ), Eindhoven, The Netherlands.
|
| pubmed:publicationType |
Journal Article
|