Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1998-9-16
pubmed:abstractText
Chagas' disease is a common cause of morbidity in Latin American countries. In Brazil, naturally occurring transmission of its etiologic agent, Trypanosoma cruzi, has been almost completely abolished through effective control programs aimed at the triatomid insect vector. Thus, transfusion of blood from infected donors has become the major route for contracting Chagas' disease due to the socioeconomically motivated migration of residents from areas where the disease is endemic to the larger urban centers. Therefore, the employment of screening tests is mandatory for all blood banks throughout the country. We compared the diagnostic performances of three commercially available screening assays used in routine testing in Brazilian blood banks: the Abbott Chagas antibody enzyme immunoassay (Abbott Laboratórios do Brasil, São Paulo), the BIOELISACRUZI kit (Biolab-Mérieux, Rio de Janeiro, Brazil), and the BIOZIMA Chagas kit (Polychaco S.A.I.C., Buenos Aires, Argentina). The evaluation was performed with sera obtained from chagasic patients and healthy residents of four different areas in Brazil where Chagas' disease is either endemic or emergent and where clinical manifestations of the disease and circulating parasite strains vary. The results obtained with each kit were compared to matched in-house enzyme-linked immunosorbent assay and immunofluorescence assay data obtained for each sample. Depending on the area under investigation, the three commercial kits produced specificity values between 93.3 and 100.0%, sensitivity values between 97.7 and 100%, and accuracies ranging from 93.6 to 100.0%.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1536382, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1538165, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-15462880, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1575289, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1662334, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1844961, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-1906650, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-2125177, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-2441341, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-2504769, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-2565018, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-3087879, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-3120255, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-3148970, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-3290679, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-4567850, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-4967348, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-5932702, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-6431222, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7559952, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7650167, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7716393, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7724232, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7810810, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7855369, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7878713, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-7923768, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8027352, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8208589, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8236424, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8527542, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8713611, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8729751, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-8758076, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-9085919, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-9196203, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-9197153, http://linkedlifedata.com/resource/pubmed/commentcorrection/9705367-9280332
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2423-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Evaluation of three commercial enzyme-linked immunosorbent assays for diagnosis of Chagas' disease.
pubmed:affiliation
Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. IMIMWAL@MICROBIO.UFRJ.BR
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't