| pubmed-article:9704935 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1539477 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:9704935 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:9704935 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9704935 | pubmed:dateCreated | 1998-8-18 | lld:pubmed |
| pubmed-article:9704935 | pubmed:abstractText | In HIV-1-infected individuals, Fas expression and Fas/FasL-mediated apoptosis of mature T cells are known to increase compared with those in normal individuals. To elucidate a relation between acute HIV-1 infection and the regulation of Fas/FasL system upon T-cell activation, resting CD4+ T cells were acutely infected or uninfected with HIV-1 and subsequently activated by phorbol myristate acetate and ionomycin (PMA/IM). Four days after infection, when HIV-1 env gp120 is expressed in more than one half of activated T cells, Fas/FasL expression was analyzed by flow cytometry, and apoptosis-inducing activity of these activated primary CD4+ T cells on Fas+ Jurkat cells was examined. The level of Fas or FasL expression was not altered during acute HIV-1 infection. The enhanced apoptosis-inducing activity upon HIV-1 infection was observed in some individuals, but its activity was not Fas/FasL-mediated. These results indicate that HIV-1 infection is not necessarily associated with either upregulation of Fas/FasL expression or Fas/FasL-mediated apoptosis. | lld:pubmed |
| pubmed-article:9704935 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9704935 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9704935 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9704935 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:9704935 | pubmed:issn | 1077-9450 | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:YagiTT | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:TanakaMM | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:NagataSS | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:TakemoriTT | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:YasudaSS | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:KuriyamaTT | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:SugimotoAA | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:YagitaHH | lld:pubmed |
| pubmed-article:9704935 | pubmed:author | pubmed-author:Tsunetsugu-Yo... | lld:pubmed |
| pubmed-article:9704935 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9704935 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:9704935 | pubmed:volume | 18 | lld:pubmed |
| pubmed-article:9704935 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9704935 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9704935 | pubmed:pagination | 307-15 | lld:pubmed |
| pubmed-article:9704935 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:9704935 | pubmed:meshHeading | pubmed-meshheading:9704935-... | lld:pubmed |
| pubmed-article:9704935 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9704935 | pubmed:articleTitle | Fas/FasL interaction is not involved in apoptosis of activated CD4+ T cells upon HIV-1 infection in vitro. | lld:pubmed |
| pubmed-article:9704935 | pubmed:affiliation | Department of Immunology, AIDS Research Center, National Institute of Infectious Disease, Tokyo, Japan. | lld:pubmed |
| pubmed-article:9704935 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9704935 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9704935 | lld:pubmed |
