Linked Life Data

9703146

Source:http://linkedlifedata.com/resource/pubmed/id/9703146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Pt 2
pubmed:dateCreated
1998-8-27
pubmed:abstractText
The classic definition of a nevus depigmentosus is a stable congenital leukoderma that may be localized, segmental, or less often, systematized. Herein we report 2 patients whose achromic nevi underwent an unusual change--the development of multiple lentigines. The lentigines ranged in size from 3 to 5 mm and the majority had an irregular outline. Although their color was darker than that of the normal surrounding skin, the most striking clinical finding was their limited distribution. The lentigines were present only within the confines of the nevus depigmentosus. They first appeared at age 3 years in 1 child and at age 1 year in the second. No new pigmented macules were noted in the older child after age 10 years and, by that time, greater than 90% of the nevus depigmentosus was "repigmented." One possible explanation would be the reversion of a mutation in 1 of the genes involved in pigmentation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0190-9622
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
330-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The development of lentigines within segmental achromic nevi.
pubmed:affiliation
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
pubmed:publicationType
Journal Article, Case Reports