|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1998-8-19
|
|
pubmed:abstractText |
Graft-infiltrating T-cell (GIC) lines cultured from biopsies obtained during acute renal allograft rejection exhibit donor-specific cytotoxicity toward proximal tubular epithelial cell (PTEC) lines cultured from corresponding biopsies. This system allows for study of the relative contributions of perforin/granzyme B (GrB)- and Fas ligand (FasL)-based cytotoxicity to killing of PTEC.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0041-1337
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
27
|
|
pubmed:volume |
66
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
259-64
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9701275-Acute Disease,
pubmed-meshheading:9701275-Adult,
pubmed-meshheading:9701275-Aged,
pubmed-meshheading:9701275-Cells, Cultured,
pubmed-meshheading:9701275-Cytotoxicity, Immunologic,
pubmed-meshheading:9701275-Fas Ligand Protein,
pubmed-meshheading:9701275-Female,
pubmed-meshheading:9701275-Graft Rejection,
pubmed-meshheading:9701275-Humans,
pubmed-meshheading:9701275-Kidney Transplantation,
pubmed-meshheading:9701275-Killer Cells, Lymphokine-Activated,
pubmed-meshheading:9701275-Male,
pubmed-meshheading:9701275-Membrane Glycoproteins,
pubmed-meshheading:9701275-Middle Aged,
pubmed-meshheading:9701275-Perforin,
pubmed-meshheading:9701275-Pore Forming Cytotoxic Proteins,
pubmed-meshheading:9701275-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:9701275-Transplantation, Homologous
|
|
pubmed:year |
1998
|
|
pubmed:articleTitle |
Mechanisms of lymphocyte-mediated cytotoxicity in acute renal allograft rejection.
|
|
pubmed:affiliation |
Renal Transplant Unit, Academic Medical Center, University of Amsterdam, The Netherlands.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
