Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-10-13
pubmed:abstractText
The encrustation and blockage of four types of urinary catheters was studied in a simple laboratory model of the catheterized bladder. Pooled human urine was supplied to the bladder chamber at 0.5 mL/min. The bladder urine was inoculated with a clinical strain of Proteus mirabilis that had been isolated from an encrusted catheter. The models were operated until the catheters blocked and atomic absorption spectrometry was used to assess the amounts of calcium and magnesium deposited on the catheters. Scanning electron microscopy was also used to locate and assess the degree of encrustation. All catheters blocked rapidly, the mean times to blockage ranging from 17.7 h (silver-coated latex), 34 h (hydrogel-coated latex), 38 h (silicone-coated latex) to 47 h (all silicone). The internal diameters of the latex catheters were only 1.5 mm compared to the 2.5 mm of the all-silicone catheters. The calcium and magnesium salts were deposited on the lumenal surfaces along the full length of catheters but occurred most extensively just below the eye-holes. There is clearly a need to develop catheter surfaces which resist encrustation by crystalline biofilms of P. mirabilis.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0195-6701
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Encrustation of indwelling urethral catheters by Proteus mirabilis biofilms growing in human urine.
pubmed:affiliation
School of Pure and Applied Biology, University of Wales, Cardiff, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't