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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1998-9-4
|
| pubmed:abstractText |
The etiology of fulminant non-A, non-B hepatitis has remained unclear, even after the identification of hepatitis C and E viruses. To study the possible involvement of hepatitis B, C, D, and E virus infections, viral genomes were amplified by a sensitive polymerase chain reaction method in sera and liver tissues obtained from 20 patients serologically diagnosed with non-A, non-B fulminant hepatitis (n = 14), acute hepatitis severe type (n = 2), and ordinary acute hepatitis (n = 4). Hepatitis C or E virus RNA could not be detected in sera obtained at admission from these patients. Hepatitis B virus DNA was detected in sera from 3 patients with fulminant hepatitis and in liver from 9 patients with fulminant hepatitis or acute hepatitis severe type. These results suggest that HCV might not be involved in fulminant non-A, non-B hepatitis, and HBV might be related to some of the serologic "non-A, non-B" viral hepatitis cases in Japan.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
178
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-33
|
| pubmed:dateRevised |
2006-4-13
|
| pubmed:meshHeading |
pubmed-meshheading:9697711-Adult,
pubmed-meshheading:9697711-Aged,
pubmed-meshheading:9697711-Amino Acid Sequence,
pubmed-meshheading:9697711-Child,
pubmed-meshheading:9697711-DNA, Viral,
pubmed-meshheading:9697711-Female,
pubmed-meshheading:9697711-Hepacivirus,
pubmed-meshheading:9697711-Hepatitis, Viral, Human,
pubmed-meshheading:9697711-Hepatitis Antibodies,
pubmed-meshheading:9697711-Hepatitis B Core Antigens,
pubmed-meshheading:9697711-Hepatitis B virus,
pubmed-meshheading:9697711-Hepatitis Delta Virus,
pubmed-meshheading:9697711-Hepatitis E virus,
pubmed-meshheading:9697711-Hepatitis Viruses,
pubmed-meshheading:9697711-Humans,
pubmed-meshheading:9697711-Japan,
pubmed-meshheading:9697711-Liver,
pubmed-meshheading:9697711-Male,
pubmed-meshheading:9697711-Middle Aged,
pubmed-meshheading:9697711-Molecular Sequence Data,
pubmed-meshheading:9697711-Polymerase Chain Reaction,
pubmed-meshheading:9697711-RNA, Viral,
pubmed-meshheading:9697711-Sequence Analysis, DNA
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Etiologic considerations of fulminant non-A, non-B viral hepatitis in Japan: analyses by nucleic acid amplification method.
|
| pubmed:affiliation |
First Department of Medicine, Chiba University School of Medicine, Japan.
|
| pubmed:publicationType |
Journal Article
|