Linked Life Data

9696284

Source:http://linkedlifedata.com/resource/pubmed/id/9696284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-10-13
pubmed:abstractText
Under light urethane anesthesia, animals cycle through patterns of EEG activity which superficially appear like waking, light sleep and slow-wave sleep patterns (States I, II and III, respectively) in unanesthetized animals. The present study questioned whether similar cortical activity patterns in anesthetized and unanesthetized golden mantled ground squirrels represented analogous states in terms of cardiorespiratory function. Sleep exerted a strong negative influence on breathing frequency and ventilation, but had less consistent effects on tidal volume. Urethane-anesthetized animals demonstrated exactly the same alterations in respiratory variables when switching between states with similar cortical activity. Cardiovascular function was also affected by arousal state; heart rate decreased and variation increased significantly as animals moved from wake into sleep. Although urethane anesthesia greatly increased heart rate and abolished respiratory sinus arrhythmia, state-dependent changes in heart rate were still evident. Overall, the states observed under urethane anesthesia mimicked sleep/wake in terms of their effect on cardio-respiratory function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0034-5687
pubmed:author
pubmed:issnType
Print
pubmed:volume
112
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
71-81
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Cortical activation states in sleep and anesthesia. I: Cardio-respiratory effects.
pubmed:affiliation
Department of Zoology, University of British Columbia, Vancouver, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't