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pubmed-article:9689985pubmed:abstractTextThe hematopoietic growth factor filgrastim has been shown to reduce both chemotherapy-induced myelosuppression and mucosal toxicities. The aim of this study was to conduct four separate pilot trials to determine the maximum-tolerated doses at which interferon alpha (IFN alpha) followed by 5-fluorouracil (5-FU) could be administered in combination with filgrastim support.lld:pubmed
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pubmed-article:9689985pubmed:articleTitleClinical trial of weekly intensive therapy with 5-fluorouracil on two different schedules combined with interferon alpha-2a and filgrastim in patients with advanced solid tumors: Eastern Cooperative Oncology Group Study P-Z991.lld:pubmed
pubmed-article:9689985pubmed:affiliationAlbert Einstein Cancer Center, Bronx, New York, USA.lld:pubmed
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