rdf:type |
|
lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0016360,
umls-concept:C0021734,
umls-concept:C0030705,
umls-concept:C0086960,
umls-concept:C0087111,
umls-concept:C0205179,
umls-concept:C0205195,
umls-concept:C0210630,
umls-concept:C0280100,
umls-concept:C0332174,
umls-concept:C1512162,
umls-concept:C1554217,
umls-concept:C2603343
|
pubmed:issue |
4
|
pubmed:dateCreated |
1998-10-14
|
pubmed:abstractText |
The hematopoietic growth factor filgrastim has been shown to reduce both chemotherapy-induced myelosuppression and mucosal toxicities. The aim of this study was to conduct four separate pilot trials to determine the maximum-tolerated doses at which interferon alpha (IFN alpha) followed by 5-fluorouracil (5-FU) could be administered in combination with filgrastim support.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1081-4442
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
261-8
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:9689985-Adult,
pubmed-meshheading:9689985-Aged,
pubmed-meshheading:9689985-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9689985-Drug Administration Schedule,
pubmed-meshheading:9689985-Female,
pubmed-meshheading:9689985-Fluorouracil,
pubmed-meshheading:9689985-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:9689985-Humans,
pubmed-meshheading:9689985-Interferon-alpha,
pubmed-meshheading:9689985-Male,
pubmed-meshheading:9689985-Middle Aged,
pubmed-meshheading:9689985-Neoplasm Metastasis,
pubmed-meshheading:9689985-Neoplasms,
pubmed-meshheading:9689985-Pilot Projects,
pubmed-meshheading:9689985-Recombinant Proteins
|
pubmed:articleTitle |
Clinical trial of weekly intensive therapy with 5-fluorouracil on two different schedules combined with interferon alpha-2a and filgrastim in patients with advanced solid tumors: Eastern Cooperative Oncology Group Study P-Z991.
|
pubmed:affiliation |
Albert Einstein Cancer Center, Bronx, New York, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study
|